Caab: what is it for and what are the adverse effects?

With the advances in medicine, medicines have become increasingly specific.

This is what happens with Caab, a medication for the treatment of advanced prostate cancer .

Although not very accessible due to its high cost, it is a good possibility for the successful treatment of the disease, considered serious.


What is Caab?

Caab is the commercial name of the active principle cabazitaxel, drug used in the treatment of cancer metastatic hormone-refractory prostate and manufactured by pharma Accord.

The medicine is applied as an injection and is used together with medicines such as prednisone or prednisolone – used as anti-inflammatories and in the treatment of autoimmune diseases – and is indicated for patients previously treated with medications containing Docetaxel.

What is the drug Caab for?

Caab is used for the treatment of hormone-resistant metastatic prostate cancer.

We call metastatic cancer the stage when cancer tumors fail to reach only the site that originated and start to spread to other organs in the body.

The hormone-resistant nomenclature is related to the body’s non-response to androgen deprivation therapy treatments – in which the levels of male hormones in the body are reduced with the use of medicines.

The drug acts on cellular processes, preventing tumor cells from completing the multiplication process, decreasing their dissemination in the body.

How should I use it?

The drug is used via intravenous infusion. The package insert is for a dose of 25mg / m² (ie, based on body surface) to be administered for 1 hour, every 3 weeks.

Combined with this application, oral intake of 10mg of prednisone (or prednisolone) is recommended daily during treatment.

The application must be prepared and administered only by a qualified professional.

Is Caab a high-cost drug?

-Yeah . Caab is part of the group of high-cost drugs.

This type of medicine, which, as the name says, has a high price, generally inaccessible to people. Some active ingredients are provided by SUS and can be withdrawn with an average indication.

At other times, court orders must be filed to gain access to treatment.

Is Caab released by Anvisa?

-Yeah . The Caab is duly registered by the National Health Surveillance Agency (ANVISA) and has its registration valid until the year 2023.

O SUS fornece o Caab?

No . The drug Caab is not part of the National List of Essential Medicines Rename or the list of exceptional drugs of 2019, which indicate which substances are provided by SUS in a protocol.

Despite this, it is worth mentioning that treatments can be achieved through legal proceedings. In such cases, it is necessary to make a request and submit a judicial quote.

To assist this process, you can count on the personalized service of advising on quotations of high-cost medications. Just access this link and fill out the form!

What are the adverse effects of Cabazitaxel?

As with other medications, the use of the active ingredient cabazitaxel can have side effects on the person being treated. Among the main adverse effects are:

  • Neutropenia – decrease in neutrophils in the blood;
  • Anemia – a decrease in red blood cells in the blood;
  • Leukopenia – decrease in white blood cells in the blood;
  • Thrombocytopenia – decreased platelets in the blood;
  • Diarrhea;
  • Nausea;
  • Tiredness;
  • Weakness;
  • Anorexia;
  • Constipation;
  • Back pain;
  • Joint pain;
  • Blood in the urine;
  • Lack of air;
  • Cough;
  • Hair loss;
  • Change in taste.

It is important to note that not all organisms react equally. That way, the symptoms will not necessarily appear in all people.

Each patient reacts in a different way to the use of the medication, with or without the reactions listed.

Price and where to buy

The Caab costs about R $ 18,000 and can be found in physical pharmacies. The Medication can also be evaluated in price comparators, such as the Consultações Remédios.

Are you similar or generic?

-Yeah . The use of the active ingredient cabazitaxel is not exclusive to Caab.

There are also similar ones such as Jevtana , produced by Sanofi-Aventi, Pro a zitax , produced by Eurofarma.

The three generic options are: Cabazitaxel Accord Farma , Cabazitaxel Doctor Reddy’s and Cabazitaxel Eurofarma .

According to the INCA, considering the data from Brazil, prostate cancer is the second most common type among men, causing more than 15 thousand deaths annually.

With the use of medications like Caab, its treatment is made possible. The Healthy Minute provides further information on high-cost medicines and disease treatments. Check out!